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. 2023 Dec 28;15(12):e51228. doi: 10.7759/cureus.51228

Figure 2. Non-conventional axis (ACE2/ANG1-7/MasR axis) and AKI progression.

Figure 2

Copyright/license: This figure has been modified from an open-source article [138] distributed under the terms and conditions of the Attribution-NonCommercial-NoDerivs 4.0 International license (CC BY-NC-ND 4.0 DEED). 

ACE2: angiotensin converting enzyme 2; AKI: acute kidney injury; ANG1–7: angiotensin (1–7); ANGII: angiotensin II; AT1R: angiotensin II type 1 receptor; CXCL1: chemokine (C-X-C motif) ligand 1; GFR: glomerular filtration rate; MasR: Mas receptor; MDA: malondialdehyde.