Table 2.
Clinical characteristics of patients infected with K. pneumoniae
| Risk factors | Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| CRKP (n = 140) | CSKP (n = 171) | P | OR (95% CI) | P | |
| Age (years) | 63.6 18.7 | 63.7 16.3 | 0.949 | ||
| Male, n (%) | 91 (65.0%) | 120 (70.2%) | 0.333 | ||
| Smoking | 30 (21.4%) | 41 (24.0%) | 0.596 | ||
| Comorbidities, n (%) | |||||
| Diabetes | 45 (32.1%) | 51 (29.8%) | 0.661 | ||
| Hypertension | 73 (52.1%) | 70 (40.9%) | 0.049 | 1.824 (1.053–3.161) | 0.032 |
| Liver abscess | 4 (2.9%) | 12 (7.0%) | 0.099 | ||
| Respiratory failure | 31 (22.1%) | 25 (14.6%) | 0.086 | ||
| Cancer | 19 (13.6%) | 40(23.4%) | 0.028 | 1.163 (0.545–2.480) | 0.696 |
| Neurological disorders | 78 (55.7%) | 46 (26.9%) | < 0.001 | 2.890 (1.568–5.326) | < 0.001 |
| Initial severity, n (%) | |||||
| ICU | 97 (69.3%) | 63 (36.8%) | < 0.001 | 2.099 (1.148–3.836) | 0.016 |
| Immunosuppressive conditions, n (%) | 36 (25.9%) | 51 (29.8%) | 0.446 | ||
| Antibiotic use before K. pneumoniae infection, n (%) | |||||
| Two or more antibiotics | 113 (80.7%) | 56(32.7%) | < 0.001 | 4.124 (2.142–7.939) | < 0.001 |
| Carbapenem antibiotic | 71 (50.7%) | 28 (16.4%) | < 0.001 | 2.613 (1.314–5.196) | 0.006 |
| The coexistence of carbapenem-resistant A. baumannii in clinical specimens, n (%) | 28 (20.0%) | 16 (9.4%) | 0.007 | 0.695 (0.313–1.541) | 0.370 |
|
Outcomes Death, n (%) |
33 (23.6%) | 24 (14.0%) | 0.031 | ||
OR: odds ratio; CI: confidence interval; ICU: intensive care unit. The variables with P < 0.05 screened in univariate analysis were included in multivariate logistic regression analysis