Table 3.
Analysis of associated risk factors for death associated with K. pneumoniae infection
| Risk factors | Variables | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
| Death (n = 57) | Survival (n = 254) | P | OR (95% CI) | P | |
| Age (years) | 65.9 ± 18.8 | 63.1 ± 17.1 | 0.265 | ||
| Male, n (%) | 37 (64.9%) | 174 (68.5%) | 0.601 | ||
| Smoking | 9 (15.8%) | 62 (24.4%) | 0.162 | ||
| Accompanying disease, n (%) | |||||
| Diabetes | 18 (31.6%) | 78 (30.7%) | 0.898 | ||
| Hypertension | 27 (47.4%) | 116 (45.7%) | 0.817 | ||
| Liver abscess | 1 (1.8%) | 15 (5.9%) | 0.201 | ||
| Respiratory failure | 30 (52.6%) | 26 (10.2%) | < 0.001 | 5.909 (2.911–11.996) | < 0.001 |
| Cancer | 8 (14.0%) | 51 (20.1%) | 0.294 | ||
| Neurological disorders | 25 (43.9%) | 99 (39.0%) | 0.498 | ||
| Initial severity, n (%) | |||||
| ICU | 53 (93.0%) | 107 (42.1%) | < 0.001 | 12.285 (4.180–36.109) | < 0.001 |
| Immunosuppressive conditions, n (%) | 19 (33.3%) | 68 (26.9%) | 0.329 | ||
| Antibiotic use before K. pneumoniae infection, n (%) | |||||
| Two or more antibiotics | 37 (64.9%) | 132 (52.0%) | 0.077 | ||
| Carbapenem antibiotic | 26 (45.6%) | 73 (28.7%) | 0.013 | 1.124 (0.564–2.239) | 0.739 |
| The coexistence of carbapenem-resistant A. baumannii in clinical specimens (%) | 12 (21.1%) | 32 (12.6%) | 0.099 | ||
| Co-carry rmpA, rmpA2, iroN and iucA, n (%) | 25 (43.9%) | 108 (42.5%) | 0.854 | ||