Table 1.
Symbol | Description |
---|---|
C | The number of conditions in a dataset. |
c(i) | The condition label of the ith cell. |
Gc |
Cumulative distribution function for the pseudotimes of a trajectory under condition c. It represents how cells are distributed along the different lineages. |
Hc |
Cumulative distribution function for the weights of a trajectory under condition c. It represents how cells are distributed between the different lineages. |
J | The number of genes in a scRNA-Seq dataset. |
L | The number of lineages in a trajectory. |
n | The number of cells in a scRNA-Seq dataset. |
sjlc |
The smoother that represents the gene expression pattern along lineage l for gene j in condition c. It is a smooth function estimated by tradeSeq. |
Ti |
The pseudotime for a cell i. For a trajectory with more than one lineage, this is a vector, with one value per lineage. It measures how far the cell has progressed along each lineage. |
The structure of a trajectory under condition c. It is what trajectory inference methods such as slingshot or monocle3 are trying to identify. |
|
Wi |
The weights for a cell i. For a trajectory with more than one lineage, this is a vector, with one value per lineage. It measures how close each cell is to each lineage. A weight of 1 means the cell belongs only to that lineage; a weight of 0 means the cell does not belong to that lineage. |
X |
A reduced-dimensional representation of the dataset. For example, for UMAP, this is a matrix with two columns, where each row gives the 2D coordinates of a cell in that reduced dimension. |
Y |
The count matrix. Each cell represents the expression level. of a gene (row-wise) in a cell (column-wise). |
The table provides the symbol, as well as a short explanation of what it represents. Symbols are listed in alpha-numerical order.