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. 2024 Jan 27;15:833. doi: 10.1038/s41467-024-44823-0

Table 1.

Notation

Symbol Description
C The number of conditions in a dataset.
c(i) The condition label of the ith cell.
Gc

Cumulative distribution function for the pseudotimes of a trajectory under condition c.

It represents how cells are distributed along the different lineages.

Hc

Cumulative distribution function for the weights of a trajectory under condition c.

It represents how cells are distributed between the different lineages.

J The number of genes in a scRNA-Seq dataset.
L The number of lineages in a trajectory.
n The number of cells in a scRNA-Seq dataset.
sjlc

The smoother that represents the gene expression pattern along lineage l for

gene j in condition c. It is a smooth function estimated by tradeSeq.

Ti

The pseudotime for a cell i. For a trajectory with more than one lineage,

this is a vector, with one value per lineage. It measures how far the cell

has progressed along each lineage.

Tc

The structure of a trajectory under condition c. It is what trajectory inference

methods such as slingshot or monocle3 are trying to identify.

Wi

The weights for a cell i. For a trajectory with more than one lineage,

this is a vector, with one value per lineage. It measures how close each cell is

to each lineage. A weight of 1 means the cell belongs only to that lineage;

a weight of 0 means the cell does not belong to that lineage.

X

A reduced-dimensional representation of the dataset. For example, for UMAP,

this is a matrix with two columns, where each row gives the 2D coordinates of a cell

in that reduced dimension.

Y

The count matrix. Each cell represents the expression level.

of a gene (row-wise) in a cell (column-wise).

The table provides the symbol, as well as a short explanation of what it represents. Symbols are listed in alpha-numerical order.