Fig. 1.
CL-43 increased the sensitivity of A549 cells to etoposide in vivo. A Balb/c nude mice were injected with 106 A549luc cells and were divided for four groups starting from day 10 after injection, when the tumors became palpable: ‘Contr’, ‘Eto’, ‘Cl-43’ and ‘Comb’(n = 6 in each group) and treatment was started. Tumor volume was measured twice a week; B Mice were weighed on Day “0” and then continued to be weighed twice a week until the end of the experiment. C A549luc tumor growth was estimated using IVIS Spectrum imaging system on day 32; D Luminescence count of tumor lesions. ** p < 0.001