Table 2:
Weight, %mBMI, EDE-Q global scores, resumption of menses and rehospitalizations by diagnosis at study timepoints
Atypical AN (N=48) |
AN (N=63) |
Mean difference 95% CI | p-value | Effect size | |
---|---|---|---|---|---|
Discharge weight (kg) | 54.3 (7.7) | 44.5 (5.3) | −9.8, −12.4 to −7.2 | <.001 | −1.52 |
12 mo. weight (kg) | 59.4 (8.2) | 50.8 (7.1) | −8.6, −11.7 to −5.6 | <.001 | −1.14 |
Weight gain over follow-up (kg) | 4.7 (7.6) | 6.1 (5.7) | 1.4, −1.3 to 4.0 | .15 | .21 |
%mBMI gain over follow-up | 5.8 (11.8) | 9.2 (10.1) | 3.4, −1.0 to 7.8 | .13 | .32 |
Weight suppression 12 mo. (%) | 16.6 (16.9) | 11.1 (12.7) | −5.5, −11.7 to .7 | .08 | −.38 |
Average %mBMI* over time | |||||
Discharge | 98.3 (8.9) | 82.3 (5.3) | −16.1, −19.0 to −13.2 | <.001 | −2.26 |
3 mo. | 103.0 (9.1) | 89.5 (9.4) | −13.5, −17.3 to −9.8 | <.001 | −1.46 |
6 mo. | 104.5 (11.6) | 90.7 (10.0) | −13.8, −18.2 to −9.4 | <.001 | −1.29 |
12 mo. | 103.9 (10.5) | 91.7 (10.9) | −12.2, −16.6 to −7.9 | <.001 | −1.14 |
Change in %mBMI over time | .02 ** | ||||
EDE-Q global score ***, mean (SD) | |||||
Admission | 3.80 (1.66) [N=41] |
3.06 (1.65) [N=56] |
−.74, −1.4 to −.1 | .03 | −.45 |
3 mo. | 2.0 (1.7) [N=34] |
2.6 (1.7) [N=43] |
.55, −.2 to 1.3 | .16 | .33 |
6 mo. | 1.7 (1.5) [N=31] |
2.1 (1.7) [N=36] |
.35, −.4 to 1.1 | .38 | .22 |
12 mo. | 1.9 (1.6) [N=33] |
2.7 (1.5) [N=44] |
.76, .1 to 1.5 | .04 | .49 |
Change in EDE-Q over time | .41 ** | ||||
Resumption of Menses | |||||
Proportion with resumption of menses | 16/20 (80%) | 20/26 (77%) | .80 | .07 | |
Rehospitalizations | |||||
Proportion rehospitalized over 12 mo. | 14/48 (29.2%) | 22/58 (37.9%) | .41 | .19 | |
Days spent rehospitalized | 7.7 (16.0) | 3.0 (6.7) | 4.7, .1 to 9.3 | .06 | .37 |
%mBMI = percent median BMI
p-value from linear mixed effect models (LMM)
EDE-Q = Eating Disorder Examination Questionnaire
Estimate of effect size: Cohen’s d =.2 (small effect); d =.5 (moderate effect); d ≥.8 (large effect)