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. Author manuscript; available in PMC: 2024 Nov 1.
Published in final edited form as: J Pediatr. 2023 Jul 28;262:113648. doi: 10.1016/j.jpeds.2023.113648

Table 3a.

Systemic saturation characteristics

Median SpO2, (IQR) Changea P valuea Median systemic hypoxia burden, (IQR) Changea P valuea
Invasive 92 (91, 94) −1.9% <0.01 4% (1–10) +4.1% <0.01
NIPPV 94 (92, 96) −1.0% <0.01 2% (0–5) +1.7% <0.01
CPAP, bubble CPAP 95 (93, 97) ref 1% (0–2) ref
High-flow NC (≥ 2 LPM) 94 (93, 96) +0.1% 0.95 1% (0–4) 0 0.94
Low-flow NC (< 2 LPM) 95 (93, 97) −0.1% 0.83 2% (0–5) +1% 0.46
No respiratory support 96 (95, 98) −0.24% 0.39 0% (0–1) +1% 0.18

Footnotes: IQR=interquartile range.

a

Change and pvalues represent estimated departure from reference (CPAP in all cases) in mixed-model regression analysis, using subject ID as random effect and accounting for repeated measures.