Table 3.
Unadjusted^ polygenic risk scores for European Ancestry set.
| OR (95% CI) | Standard Error | p-value | Corrected* p-value |
|
|---|---|---|---|---|
| Depression | 1.260 (0.986, 1.610) | 0.1251 | 0.0651 | 0.1042 |
| Anxiety | 1.543 (1.192, 1.997) | 0.1318 | 0.0010 | 0.0020 |
| Bipolar Disorder | 1.771 (1.361, 2.304) | 0.1343 | 0.00002 | 0.00008 |
| Cross Disorders | 1.859 (1.414, 2.444) | 0.1396 | 0.000009 | 0.00007 |
| Schizophrenia SDs | 1.713 (1.297, 2.261) | 0.1418 | 0.0002 | 0.0004 |
| Alzheimer’s Disease | 1.061 (0.815, 1.342) | 0.1278 | 0.6459 | 0.8612 |
| Autism Spectrum Disorders | 1.046 (0.815, 1.342) | 0.1270 | 0.7235 | 0.8269 |
| Obsessive Compulsive Disorder | 1.006 (0.786, 1.287) | 0.1259 | 0.9646 | 0.9646 |
polygenic scores were adjusted for age, sex, race, and ancestral principal components, but were not adjusted for a history of that disorder.
Corrected using Benjamini-Hochberg Adjusted p-value