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. Author manuscript; available in PMC: 2025 Jan 1.
Published in final edited form as: Schizophr Res. 2023 Jul 28;263:178–190. doi: 10.1016/j.schres.2023.07.015

Table 6.

Adjusted^ polygenic risk scores for African Ancestry set.

OR (95% CI) Standard Error p-value Corrected*

p-value
Depression 1.218 (0.748, 1.982) 0.2486 0.428 1
Anxiety 1.032 (0.660, 1.614) 0.2281 0.8907 1
Bipolar Disorder 1.709 (1.025, 2.850) 0.2609 0.0399 0.3192
Cross Disorders 1.390 (0.441, 4.380) 0.5854 0.5735 1
Schizophrenia SDs 1.168 (0.582, 2.344) 0.3556 0.6630 1
Alzheimer’s Disease 1.469 (0.936, 2.303) 0.2297 0.0943 0.3772
Autism Spectrum Disorders 1.054 (0.660, 1.682) 0.2386 0.826 1
Obsessive Compulsive Disorder 0.974 (0.633, 1.499) 0.2200 0.905 0.9050
^

polygenic scores were adjusted for a history of that mental illness, for example: depression scores were adjusted for a history of depression as indicated by ICD 9 and 10 codes for depression, anxiety was adjusted for a history of anxiety according to ICD 9 and 10 codes for anxiety, etc. For cross disorders, all ICD 9 and 10 covariates (depression, anxiety, schizophrenia spectrum disorders, Alzheimer’s disease, autism spectrum disorders, obsessive compulsive disorder and a composite covariate representing all other mental health codes not represented by the ones listed above was included.)

*

Corrected using Benjamini-Hochberg Adjusted p-value