Figure 4.

Histology and immunohistochemistry of intestinal wall biopsies from a cat with B cell HGAL. Heavy infiltration of the lamina propria and submucosa can be seen, destroying the normal architecture of the intestine. Villous and crypt architecture is also severely altered. (a) HE stain; (b) CD3 (T cell marker) stain; (c) CD79a (B cell marker) stain. Note the heavy staining of the neoplastic B cell infiltrate. Courtesy of Associate Professor Mark Krockenberger (image a) and Dr Katherine Briscoe (images b and c), University of Sydney