Table 5.
Selected psychopharmacological agents that may be useful in the treatment of feline behavioral diagnoses
| Alprazolam (tablets: 0.25, 0.5, 1, 2 mg [1 and 2 mg tablets scored]) | 0.0125–0.025 mg/kg po q. 12 h (or at high end dose 1/4 0.25 mg tablet for a 3 kg cat) |
| Amitriptyline (tablets: 10, 25, 50, 75, 100, 150 mg) | 0.5–2.0 mg/kg po q. 12–24 h; start at 0.5 mg/kg po q. 12 h |
| * Clomipramine (capsules: 25, 50, 75 mg in human formulation [Anafranil]; 20, 40, 80 mg scored tablets in veterinary formulation [Clomicalm/Novartis][5 mg scored tablets available in Australia and Europe]) | 0.5 mg/kg po q. 24 h |
| Clonazepam (tablets: 0.125, 0.25, 0.5, 1.0, 2.0 mg) | 0.1–0.2 mg/kg po q. 12–24 h |
| Clorazepate (tablets: 3.75, 7.5, 11.25, 15, 22.5; capsules: 3.75, 7.5, 15 mg) | 0.5–2.2 mg/kg po prn for profound distress; 0.2–0.4 mg/kg q. 12–24 h |
| Diazepam (tablets: 1, 2, 5, 10 mg; solution: 5 mg/ml) | 0.2–0.4 mg/kg po q. 12–24 h (start at 0.2 mg/kg po q. 12 h) |
| Doxepin (capsules: 10, 25, 50, 75, 100, 150 mg; solution: 10 mg/ml) | 0.5–1.0 mg/kg po q. 12–24 h (start low) |
| Fluoxetine (capsules: 10, 20 mg; solution: 5 mg/ml) | 0.5–1.0 mg/kg po q. 24 h |
| Fluvoxamine (capsules: 10, 20 mg) | 0.25–0.5 mg/kg po q. 24 h |
| Imipramine (tablets: 10, 25, 50 mg; capsules 75, 100, 125, 150 mg) | 0.5–1.0 mg/kg po q. 12–24 h (start at 0.5 mg/kg po q. 12 h) |
| Nortriptyline (capsules: 10, 25, 50, 75 mg) | 0.5–2.0 mg/kg po q. 12 −24 h |
| Oxazepam (tablets: 15 mg; capsules: 10, 15, 30 mg) | 0.2–0.5 mg/kg po q. 12–24 h; high dose:1.0–2.5 mg/kg po q. 12–24 h; 3 mg/kg po as a bolus for appetite stimulation |
| Paroxetine (tablets: 10, 20, 30, 40 mg; suspension: 10 mg/5 ml) | 0.5 mg/kg po q. 24 h×6–8 weeks to start |
| Protriptyline (tablets: 5, 10 mg) | 0.5–1.0 mg/kg po q. 12–24 h (start at 0.5 mg/kg po q. 12 h) |
| Selegiline (tablets: 5, 10, 15, 30 mg [Anipryl/ Pfizer; Selgan/Sanofi/CEVA]) | 0.25–0.5 mg/kg po q. 12–24 h; start low |
| Sertraline (tablets: 25, 50, 100 mg) | 0.5 mg/kg po q. 24 h×6–8 weeks to start |
| Triazolam (tablets: 0.125, 0.25 mg) | 2.5–5 mg/cat po q. 8 h |
*
Veterinary label for some canine and feline conditions; label depends on country and species.