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. 2023 Dec 29;15(12):e51299. doi: 10.7759/cureus.51299

Table 1. Food and Drug Administration (FDA)-approved artificial sweeteners, their sweetness compared to table sugar, common side effects, and associated cancer risk.

*: Few studies suggest an association with cancer risk in rodents, but not humans.

**: Sweetness compared to table sugar.

Artificial sweetener FDA approval Sweetness** Cancer risk
Aspartame 1974 200 None*
Saccharin 1977 300 None
Acesulfame potassium 1988 200 None
Sucralose 1998 600 None
Neotame 2002 7,000–13,000 None
Advantame 2014 20,000 None