Table 3.

Associations Between Gene Polymorphisms and Renal Function

Genes	N	Creatinine (mol/L) median (range)	p
CYP4F2 (rs2108622)			0.316
CC	111	84 (42–480)
CT	60	82 (41–211)
TT	13	69 (49–115)
T allele	86	81 (41–211)	0.358
C allele	282	84 (41–480)
CYP4F2 (rs1558139)			0.592
AA	36	80 (49–211)
AG	104	84 (41–455)
GG	44	86 (42–480)
A allele	176	83 (41–455)	0.564
G allele	192	85 (41–480)
CYP4F2 (rs3093135)			0.345
AA	28	85 (42–114)
AT	104	83 (50–480)
TT	52	86 (41–211)
A allele	160	84 (42–480)	0.289
T allele	208	83 (41–480)
CYP4F2 (rs2074902)			0.595
CC	6	77 (49–115)
CT	51	84 (41–211)
TT	127	84 (42–480)
T allele	305	84 (41–480)	0.323
C allele	63	84 (41–211)
CYP2C19 (rs4244285) (*2)			0.752
AA	2	104 (98–110)
AG	38	86 (42–124)
GG	144	84 (41–480)
A allele	42	86 (42–124)	0.276
G allele	326	84 (41–480)
ABCB1 (rs1045642)			0.014
CC	48	75 (41–480)
CT	101	84 (42–455)
TT	35	87 (56–211)
T allele			0.007
Absent (CC)	197	75 (41–480)
Present (CT and TT)	171	85 (42–455)
FBG-C148T (rs1800787)			0.779
TT	21	87 (49–212)
CT	71	84 (49–480)
CC	92	82 (41–455)
T allele	113	84 (49–480)	0.573
C allele	255	83 (41–480)
COX-2 (rs689465)
CC	2	77 (53–100)
CT	30	86 (59–455)	0.147
TT	151	83 (41–480)
T allele	332	84 (41–480)	0.098
C allele	34	85 (51–455)
PAI-1 (rs5918)			0.93
CC	7	80 (60–212)
CT	65	84 (48–211)
TT	112	84 (41–480)
T allele	289	84 (41–480)	0.769
C allele	79	84 (48–212)
CYP2C19 (rs12248560) (*17)			0.389
CC	97	84 (41–480)
CT	76	84 (42–212)
TT	11	70 (59–98)
T allele	98	84 (42–212)	0.279
C allele	270	84 (41–480)

Notes: Values are median (range) unless indicated otherwise.