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. 2023 Nov 16;115(1):155–169. doi: 10.1111/cas.16014

FIGURE 3.

FIGURE 3

MicroRNA (miR)‐296‐3p promotes ovarian cancer development in vitro and in vivo. (A, B) Effects of miR‐296‐3p on the proliferation of A2780 and SKOV3 cells were detected by EdU assays. (C, D) Cell colony‐forming ability was measured using colony formation assay. (E, F) Effects of miR‐296‐3p on the migration of A2780 and SKOV3 cells were determined with Transwell migration assays. (G, H) Representative images from Transwell invasion assays of A2780 and SKOV3 cells. (I, J) A2780 cells transfected with miR‐296‐3p or anti‐miR‐296‐3p and their negative control were used to establish s.c. xenograft tumors (n = 7). Tumor growth curves and tumor weights are shown. (K, L) Effects of miR‐296‐3p on the tumor growth of SKOV3 cells in nude mice (n = 7). *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001.