Table 4. In Vivo PK Data in Rats: Compound 14 and 20.

compd	In vivo PK rat
14	CLblood = 0.50 L/h/kg, t1/2 = 2.9 h, Vss = 1.6 L/kg, F = 41%
20	CLblood = 0.31 L/h/kg, t1/2 = 2.9 h, Vss = 1.3 L/kg, F = 46%