Table 6. In Vivo PK Data from Rats for Compounds 30, 31, and 33.

compd	in vivo PK rat
30	CLblood = 1.99 L/h/kg, t1/2 = 0.8 h, Vss = 1.4 L/kg, F = 40%
31	CLblood = 0.43 L/h/kg, t1/2 = 3.6 h, Vss = 1.8 L/kg, F = 58%
33	CLblood = 2.3 L/h/kg, t1/2 = 0.9 h, Vss = 1.8 L/kg, F = 76%