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. 2024 Jan 17;67(2):1225–1242. doi: 10.1021/acs.jmedchem.3c01714

Table 7. Comparison of Matched Pairs Based on Indazole and Benzimidazole Core.

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a

Biochemical potency of IRAK4 inhibition (1 mM ATP).

b

Biochemical potency of FLT3 inhibition (10 μM ATP).

c

Compound purity ap. 90% according to 1H NMR.

d

,eResults for the individual enantiomers with unkown absolute stereochemistry.