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. 2024 Jan 29;52:15. doi: 10.1186/s41182-024-00581-9

Table 4.

Purification profile of E. ocellatus metalloproteinase, serine protease and phospholipase A2 fractions

Venom fraction Purification step Total protein (µg) Total activity (µmol/min) Specific activity (µmol/min/mg) Purification fold Yield (%)
SVMP
Crude venom 2.36 6.40 2.71 1.00 100.00
Acetone precipitation 0.92 2.64 2.87 1.06 41.30
Ion exchange chromatography on DEAE cellulose 0.54 1.99 3.69 1.36 31.10
Gel filtration on Sephadex G-75 0.32 1.64 5.13 1.89 25.63
SVSP
Crude venom 2.36 5.42 2.22 1.00 100.00
Acetone precipitation 0.95 2.64 2.77 1.24 48.70
Ion exchange chromatography on DEAE cellulose 0.50 1.50 3.00 1.35 27.70
Gel filtration on Sephadex G-75 0.39 1.27 3.26 1.46 23.43
PLA2
Crude venom 2.36 4.73 2.00 1.00 100.00
Acetone precipitation 1.82 3.94 2.16 1.10 83.30
Ion exchange chromatography on DEAE cellulose 1.43 3.62 2.53 1.27 76.56
Gel filtration on Sephadex G-75 0.56 1.99 3.55 1.78 42.07