Table 3.
Hazard ratio (95% confidence interval) | ||||
---|---|---|---|---|
Model 1 | Model 2 | Model 3 | Model 4 | |
TyG (continuous) | P for interaction < 0.001 | P for interaction < 0.001 | P for interaction < 0.001 | P for interaction < 0.001 |
Total | 0.98 (0.86–1.11) | 1.09 (0.95–1.25) | 1.09 (0.95–1.25) | 1.05 (0.90–1.22) |
< 65 yrs |
1.55 (1.25–1.94)* P < 0.001 |
1.59 (1.27-2.00)* P < 0.001 |
1.60 (1.28-2.00)* P < 0.001 |
1.54 (1.18–2.01)* P < 0.002 |
≥ 65 yrs | 0.85 (0.72–1.01) | 0.90 (0.76–1.06) | 0.91 (0.77–1.08) | 0.92 (0.76–1.12) |
TyG (categorical) | P for interaction = 0.002 | P for interaction = 0.002 | P for interaction < 0.001 | P for interaction = 0.001 |
TyG tertile 1 | Reference | Reference | Reference | Reference |
Total | ||||
TyG tertile 2 |
0.79 (0.64–0.98)* P = 0.032 |
0.81 (0.65–0.99)* P = 0.045 |
0.87 (0.70–1.07) | 0.84 (0.68–1.05) |
TyG tertile 3 | 0.92 (0.75–1.12) | 1.06 (0.87–1.30) | 1.07 (0.87–1.32) | 1.01 (0.81–1.27) |
< 65 yrs | ||||
TyG tertile 2 | 0.94 (0.61–1.43) | 0.89 (0.58–1.36) | 0.98 (0.63–1.51) | 0.93 (0.60–1.45) |
TyG tertile 3 |
1.55 (1.07–2.24)* P = 0.020 |
1.54 (1.07–2.24)* P = 0.021 |
1.64 (1.12–2.41)* P = 0.011 |
1.44 (1.01–2.18)* P = 0.048 |
≥ 65 yrs | ||||
TyG tertile 2 |
0.72 (0.56–0.92)* P = 0.008 |
0.82 (0.64–1.04) | 0.87 (0.68–1.12) | 0.87 (0.67–1.12) |
TyG tertile 3 | 0.82 (0.64–1.05) | 0.90 (0.70–1.15) | 0.92 (0.71–1.18) | 0.94 (0.71–1.34) |
Model 1 was unadjusted
Model 2 was adjusted for age and gender
Model 3 was adjusted for age, gender, ethnicity, educational level, BMI, CHF, albumin, eGFR, UACR, insulin treatment, and metformin
Model 4 was adjusted for age, gender, ethnicity, educational level, current smoking, BMI, CHF, CAD, hypertension, albumin, LDL-C, eGFR, HbA1c, UACR, UA, Insulin treatment, metformin, and statins
*indicated that the p value was less than 0.05