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. 2024 Jan 28;23:43. doi: 10.1186/s12933-024-02120-6

Table 4.

Predictive power of various models with different IR indices (Reference = TyG model)

Base model + TyG + HOMA-IR + QUICKI + HOMA-beta + Glucose + Triglyceride
C-index
(95% CI)
C-index
(95% CI)
P value C-index
(95% CI)
P value C-index
(95% CI)
P value C-index
(95% CI)
P value C-index
(95% CI)
P value
All-cause mortality
 Total 0.80 (0.78–0.82) 0.80 (0.78–0.82) 0.477 0.80 (0.78–0.81) 0.151 0.80 (0.78–0.81) 0.302

0.80

(0.78–0.82)

0.646

0.80

(0.78–0.82)

0.356
 < 65 yrs 0.76 (0.73–0.79) 0.75 (0.72–0.79) 0.204 0.75 (0.71–0.78) 0.119 0.75 (0.71–0.78) 0.073

0.76

(0.73–0.79)

0.838

0.75

(0.72–0.79)

0.021
 ≥ 65 yrs 0.75 (0.73–0.77) (0.75 (0.73–0.77) 0.909 0.75 (0.73–0.77) 0.726 0.75 (0.73–0.77) 0.658

0.75

(0.73–0.77)

0.972

0.75

(0.73–0.77)

0.775
Cardiovascular mortality
 Total 0.82 (0.78–0.85) 0.82 (0.80–0.85) 0.982 0.82 (0.80–0.85) 0.911 0.82 (0.80–0.85) 0.882

0.82

(0.80–0.85)

0.816

0.82

(0.79–0.85)

0.404
 < 65 yrs 0.82 (0.76–0.88) 0.82 (0.75–0.88) 0.788 0.82 (0.75–0.88) 0.736 0.81 (0.75–0.88) 0.626

0.82

(0.77–0.88)

0.496

0.81

(0.75–0.87)

0.579
 ≥ 65 yrs 0.77 (0.73–0.81) 0.78 (0.74–0.81) 0.298 0.78 (0.74–0.81) 0.319 0.78 (0.74–0.81) 0.472

0.77

(0.73–0.81)

0.938

0.77

(0.73–0.81)

0.802
Cancer mortality
 Total 0.75 (0.71–0.79) 0.75 (0.71–0.79) 0.400 0.75 (0.71–0.79) 0.837 0.75 (0.71–0.79) 0.721

0.75

(0.71–0.79)

0.563

0.75

(0.71–0.79)

0.441
 < 65 yrs 0.70 (0.62–0.78) 0.70 (0.62–0.78) 0.966 0.70 (0.62–0.77) 0.793 0.69 (0.62–0.77) 0.623

0.69

(0.62–0.77)

0.831

0.71

(0.63–0.79)

0.446
 ≥ 65 yrs 0.64 (0.58–0.70) 0.64 (0.58–0.71) 0.933 0.65 (0.59–0.71) 0.834 0.65 (0.58–0.71) 0.854

0.65

(0.58–0.71)

0.760

0.64

(0.58–0.70)

0.949
Non-cardiovascular mortality
 Total 0.79 (0.77–0.81) 0.79 (0.77–0.81) 0.160 0.79 (0.77–0.81) 0.241 0.79 (0.77–0.81) 0.275

0.79

(0.77–0.81)

0.159

0.79

(0.77–0.81)

0.389
 < 65 yrs 0.75 (0.72–0.79) 0.74 (0.70–0.78) 0.598 0.74 (0.70–0.78) 0.428 0.73 (0.69–0.77) 0.177

0.73

(0.69–0.78)

0.050

0.73

(0.70–0.77)

0.043
 ≥ 65 yrs 0.74 (0.72–0.77) 0.74 (0.72–0.77) 0.700 0.74 (0.72–0.77) 0.602 0.74 (0.72–0.77) 0.698

0.74

(0.72–0.77)

0.643

0.74

(0.72–0.77)

0.853

Base models included the covariates which were selected by the stepwise method in Model 3