Table 2. Percentages of positively stained area (%) in AT1R and TGFβ1 immunohistochemical stain, and the percentage of nuclei with positive staining in 8OHdG immunohistochemical stain of the left and RVFW, IVS, and aorta.
| C group (n = 6) | P group (n = 6) | |||
|---|---|---|---|---|
| AT1R | Median (range) | Median (range) | p-value | |
| LVFW (%) | 4.00×10−2 (0.87–16.93×10−2) |
32.12×10−2 (8.50–45.80×10−2) |
0.0065 | |
| RVFW (%) | 5.32×10−2 (0.35–18.93×10−2) |
55.08×10−2 (33.37–83.63×10−2) |
0.0039 | |
| IVS (%) | 0.97×10−2 (0.32–4.27×10−2) |
25.00×10−2 (17.43–30.03×10−2) |
0.0039 | |
| AO (%) | 4.65×10−2 (0.87–21.90×10−2) |
26.00×10−2 (19.57–40.06×10−2) |
0.0064 | |
| 8OHdG | Median (range) | Median (range) | ||
| LVFW (%) | 7.24 (6.08–12.35) |
35.05 (27.37–68.50) |
0.0039 | |
| RVFW (%) | 12.21 (0–14.05) |
45.40 (32.91–63.85) |
0.0250 | |
| IVS (%) | 14.86 (0.63–22.89) |
47.30 (33.96–60.25) |
0.0039 | |
| AO (%) | 31.37 (25.37–50.98) |
51.05 (43.31–61.49) |
0.0163 | |
| TGFβ1 | Median (range) | Median (range) | ||
| LVFW (%) | 1.26 (0.43–3.24) |
4.89 (2.28–5.90) |
0.0065 | |
| RVFW (%) | 0.39 (0.28–1.14) |
4.15 (1.94–6.73) |
0.0039 | |
| IVS (%) | 0.60 (0.02–1.28) |
6.48 (3.98–9.36) |
0.0039 | |
| AO (%) | 1.45 (0.02–2.63) |
5.40 (3.84–6.96) |
0.0039 |
(8OHdG): 8-hydroxy-2’-deoxyguanosine; (AO): aorta; (AT1R): angiotensin II type 1 receptor; (C group): control group; (IVS): interventricular septum; (LVFW): left ventricular free wall; (P group): high-dose prednisolone group; (RVFW): right ventricular free wall; (TGFβ1): transforming growth factor β1.