Table 2.

Baseline characteristics of the patients

Study	Mean age (y)	Male %	Baseline NYHA class	HTN%	DM%	CAD%	MI%	Prior HF admission %
Noe et al. 1999	F - 75.1 T - 75.1	F - 54 T - 57.3	F- 2.36 T- 2.34	F - 59.1 T - 63.1	F - 33.6 T - 44.7	NA	F - 38.0 T - 45.6	NA
Stroupe et al. 2000	F - 63 T - 63	F - 35 T - 38	NA	F - 47 T - 53	F - 43 T - 40	NA	F - 3 T - 7	NA
Murray et al. 2001	F - 64.1 T - 64.1	F - 46 T - 49	F - 2.6 T - 2.8	F - 58 T - 61	F - 53 T - 46	F - 41 T - 35	F - 5 T - 12	F - 11 T - 25
Muller et al. 2003	F - 73.2 T - 74.4	F - 40.9 T - 45.1	F - 2.37 T - 2.47	F - 31.3 T - 27.1	F - 78.3 T - 72.1	NA	F - 51.3 T - 41.8	F - 7.8 T - 13.1
Yamato et al. 2003	F - 64.9 T - 64.7	F - 60 T - 56	F - 2.6 T - 2.7	F - 24 T - 28	NA	NA	F - 48 T - 52	NA
Paterna et al. 2005	F - 74.3 T- 73.5	F - 67 T - 64	NA	F - 21 T - 29	NA	F - 52 T - 50	NA	NA
TORAFIC 2011	F - 69.3 T - 68.1	F - 62 T - 55	NYHA II F - 89.7 % T - 96.1 %	F - 100 T - 100	NA	NA	NA	NA
Trippel et al. 2018	F - 69.3 T - 68	F - 39 T - 76	NYHA II F - 33 % T - 59 %	F - 94 T - 100	F - 100 T - 100	F - 39 T - 53	NA	F - 28 T - 76
Balsam et al. 2019	F - 65 T - 74	F - 83.3 T - 68.8	F - 2 T - 2	F - 58.3 T - 50	F - 50 T - 37.5	F - 45.8 T - 50	NA	F - 67.7 T - 56.3
Mentz et al. 2023	F - 65 T - 64	F - 61 T - 65.2	NA	NA	F - 47.3 T - 48.1	F - 26.7 T - 29.8	NA	F - 33.7 T - 37

CAD = coronary artery disease; DM = diabetes mellitus; F = furosemide; HF = heart failure; HTN = hypertension; MI = myocardial infarction; NA = not available; NYHA = New York Heart Association; T = torsemide; TORAFIC = torasemide prolonged release versus furosemide in patients with chronic heart failure; y = years.