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. Author manuscript; available in PMC: 2024 Jan 29.
Published in final edited form as: J Thromb Haemost. 2023 Apr 15;21(8):2236–2247. doi: 10.1016/j.jtha.2023.04.008

Figure 5:

Figure 5:

Role of Syk tyrosine kinase signaling in TEG. Blood samples were analyzed from WT mice (n=8), or WT (n=5) or PAR4mKO (n=4) mice with addition of the Syk inhibitor PRT-2607 (20 μM) 10 mins prior to TEG assay. (A-C) TEG parameters: R time (A), α-angle (B) and MA (C). (D) Representative TEG traces. Data shown as mean ± SD. Statistical significance was determined by one-way ANOVA with Tukey’s multiple comparison test (A,C) or Kruskal-Wallis test with Dunn’s multiple comparison (B). Symbols directly over bars represent significance compared to control. **P < .01, ****P < .0001.