Table 1:
Classifier | # patients | Complete response, pT0N0 n (%; 95% CI) | Downstaging* (<pT2N0) n (%; 95% CI) |
---|---|---|---|
Total | 155 | 51 (33%; 26%, 41%) | 81 (52%; 44%, 60%) |
TCGA Basal/Sq + Neuronal |
55 |
21 (38%; 25%, 52%) |
26 (47%; 34%, 61%) |
Luminal | 77 | 25 (33%; 22%, 44%) | 43 (56%; 44%, 67%) |
Luminal infiltrated | 23 | 5 (22%; 7%, 44%) | 12 (52%; 31%, 73%) |
Consensus Ba, Sq, NE |
51 |
17 (33%; 21%, 48%) |
24 (47%; 33%, 62%) |
Luminal | 80 | 27 (34%; 24%, 45%) | 46 (58%; 46%, 68%) |
Stroma-rich | 24 | 7 (29%; 13%, 51%) | 11 (46%; 26%, 67%) |
MDA Basal |
49 |
14 (29%; 17%, 43%) |
23 (47%; 33%, 62%) |
Luminal | 56 | 22 (39%; 27%, 53%) | 36 (64%; 50%, 77%) |
p53-like | 50 | 15 (30%; 18%, 45%) | 22 (44%; 30%, 59%) |
Downstaging category includes complete responders
TCGA – The Cancer Genome Atlas, Ba – Basal, Sq – Squamous, NE – neuroendocrine, MDA – MD Anderson