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. Author manuscript; available in PMC: 2024 Jul 17.
Published in final edited form as: Clin Cancer Res. 2024 Jan 17;30(2):444–449. doi: 10.1158/1078-0432.CCR-23-0602

Table 2:

Evaluating AUC in logistic models predicting pathologic response with stratification (strat) factors and molecular subtype classifiers in 155 evaluable patients

(n=155) # of Categories pT0N0 outcome Downstaging (< pT2N0)
Incremental P-value * AUC Incremental P-value* AUC
2 Strat Factors Only (PS, stage) NA 0.55 NA 0.57
Classifier plus two strat factors
TCGA 3 0.28 0.59 0.44 0.59
Consensus 3 0.98 0.54 0.10 0.61
MD Anderson 3 0.51 0.57 0.18 0.63
Dichotomous Coxen Scores plus two strat factors
ddMVAC Coxen 2 0.93 0.55 0.68 0.56
GC Coxen 2 0.18 0.60 0.23 0.62
*

2-sided p-value tests if classifier increases the AUC beyond the two stratification factors: clinical stage and PS (performance status)