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. Author manuscript; available in PMC: 2024 Jul 17.
Published in final edited form as: Clin Cancer Res. 2024 Jan 17;30(2):444–449. doi: 10.1158/1078-0432.CCR-23-0602

Table 4:

Association of Classifiers with Progression-Free and Overall Survival (n=155)

Classifier N/# deaths/# PFS events 5-yr PFS estimate PFS HR (95% CI), p-value* 5-yr OS estimate OS HR (95% CI), p-value*
TCGA
 Basal/Sq/Neuronal 55/17/24 57% 1.0 (reference) 72% 1.0 (reference)
 Luminal 77/19/28 63% 0.68(0.40, 1.18), P=0.17 75% 0.67 (0.35, 1.29), p=0.23
 Luminal inf. 23/6/7 67% 0.58 (0.25, 1.36), P=0.21 72% 0.84 (0.33, 2.13) p=0.71
Consensus
 Ba/Sq/NE 51/15/21 60% 1.0 (reference) 74% 1.0(reference)
 Luminal 80/20/29 63% 0.75 (0.43, 1.31), P=0.31 75% 0.73 (0.37, 1.43) p=0.36
 Stroma-rich 24/7/9 61% 0.84 (0.38, 1.85), P=0.67 69% 1.03 (0.42, 2.55) p=0.95
MDA
 Basal 49/14/19 62% 1.0 (reference) 75% 1.0 (reference)
 Luminal 56/14/20 65% 0.81 (0.43, 1.52), P=0.51 75% 0.73 (0.35, 1.55) p=0.41
 p53-like 50/14/20 57% 0.99 (0.53, 1.86), P=0.98 70% 0.97 (0.46, 2.03) p=0.93
*

adjusted for two stratification factors, 2-sided p value