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. 2024 Jan 29;7:136. doi: 10.1038/s42003-024-05813-6

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Thyroid inflammation was determined according to the lymphocyte infiltration area using HE staining of the mice’s thyroid gland. Scale bar: 100 μm. b The α diversity indices (Chao 1, ACE, Shannon, and Simpson indexes) of the microbiota among different iodine intake groups. c The Venn diagram illustrates the overlap of OTUs in gut microbiota among different iodine intake groups. Overlapping parts in the figure indicate common species. d Order level comparison of fecal microbiota among these four groups. e Heatmap based on the abundance of the first 35 genera among these four groups. N = 12, 10, 10, 10 for CON, IG10, IG100, and IG1000 groups respectively.