Table 1.
Baseline data at time of CP. *1 Other diagnoses included meningoencephalitis, cerebral venous sinus thrombosis and posterior reversible encephalopathy syndrome leading to diffuse cerebral edema. Age, BMI and the ability of a patient to walk were assessed at the time of CP
| Baseline data | Overall | ABFs | PMMA | PEEK | CaP-Ti | HA |
|---|---|---|---|---|---|---|
| Study population (no.) | 139 (100%) | 25/139 (18.0%) | 56/139 (40.3%) | 35/139 (25.2%) | 21/139 (15.1%) | 2/139 (1.4%) |
| Median age (years) | 54 | 54 | 53 | 58 | 45 | 55 |
| Diagnosis | ||||||
| - Stroke | 56/139 (40.3%) | 8/25 (32.0%) | 27/56 (48.2%) | 11/35 (31.4%) | 9/21 (42.9%) | 1/2 (50.0%) |
| - TBI | 41/139 (29.5%) | 9/25 (36.0%) | 16/56 (28.6%) | 9/35 (25.7%) | 7/21 (33.3%) | 0 |
| - SAH/ICH | 33/139 (23.7%) | 7/25 (28.0%) | 10/56 (17.8%) | 11/35 (31.4%) | 4/21 (19.0%) | 1/2 (50.0%) |
| - Other*1 | 9/139 (6.5%) | 1/25 (4.0%) | 3/56 (5.4%) | 4/35 (10.5%) | 1/21 (4.8%) | 0 |
| VPS prior to CP | 47/139 (33.8%) | 9/25 (36.0%) | 13/56 (23.2%) | 17/35 (48.6%) | 7/21 (33.3%) | 1/2 (50.0%) |
| Unable to walk | 82/139 (59.0%) | 13/25 (52.0%) | 29/56 (51.8%) | 29/35 (82.9%) | 9/21 (42.9%) | 2/2 (100%) |
| Median BMI (kg/m2) | 25 | 27 | 25.5 | 24 | 25 | 25 |
| Comorbidities | ||||||
| - Obesity | 18/139 (12.9%) | 2/25 (8.0%) | 18/56 (32.1%) | 3/35 (8.6%) | 3/21 (14.3%) | 0 |
| - Diabetes | 9/139 (6.5%) | 2/25 (8.0%) | 9/56 (16.1%) | 1/35 (2.9%) | 1/21 (4.8%) | 0 |
| - Coronary artery disease | 11/139 (7.9%) | 1/25 (4.0%) | 4/56 (7.1%) | 7/35 (20.0%) | 0 | |
| - Alcohol abuse | 18/139 (12.9%) | 3/25 (12.0%) | 6/56 (10.7%) | 5/35 (14.3%) | 4/21 (19.0%) | 0 |
| - Smoking | 28/139 (20.1%) | 5/25 (20.0%) | 12/56 (21.4%) | 10/35 (28.6%) | 4/21 (19.0%) | 0 |
| Anticoagulant or antiplatelet therapy | 41/139 (29.5%) | 7/25 (28.0%) | 12/56 (21.4%) | 14/35 (40.0%) | 10/21 (47.6%) | 1/2 (50.0%) |
| Median time to CP (days) | 117 | 108 | 94 | 146 | 136 | 226 |
| Median surgical time (minutes) | 106 | 174 | 98 | 87 | 108 | 168 |
| Perioperative lumbar drain | 38/139 (27.3%) | 6/25 (24.0%) | 23/56 (41.1%) | 3/35 (8.6%) | 6/21 (28.6%) | 0 |
| Median follow-up (months) | 43 | 70 | 75 | 24 | 16 | 70 |