Accurate measurement of medication adherence and drug exposure in drug trials is crucial for reliable research outcomes, but it is often overlooked compared to other aspects of the study.

Pre-electronic methods to measure adherence in trials (i.e. pill count, self-report, bioanalytical assays) are imprecise and biased.

Electronic monitoring is a precise and reliable method to capture variability in adherence behaviors, such as timing deviations, missed or extra doses, drug holidays, and discontinuation.