Table 4.
Preoperative, operative and follow-up data (n = 512).
| Variable | Total (n = 512) | Group with destruction of the aortic annulus (n = 80) | Group without destruction of the aortic annulus (n = 432) | P value |
|---|---|---|---|---|
| Preoperative | ||||
| Male, n (%) | (%) | (%) | ||
| Age, years | 40.63 ± 0.69 | 39.8 ± 1.2 | 40.78 ± 0.78 | 0.605 |
| Weight, kg | 54.69 ± 0.52 | 62.6 ± 0.58 | 53.22 ± 0.58 | <0.001 |
| Time between symptoms and surgery, months | 2.64 ± 0.11 | 2.52 ± 0.28 | 2.66 ± 0.12 | 0.638 |
| Vegetation length, mm | 10.75 ± 0.3 | 13.2 ± 0.48 | 10.3 ± 0.33 | <0.001 |
| Preoperative left ventricular end diastolic dimension, mm | 64.03 ± 0.38 | 70.6 ± 0.67 | 62.77 ± 0.40 | <0.001 |
| Preoperative left ventricular ejection fractions, % | 60.32 ± 0.37 | 59.0 ± 0.81 | 60.58 ± 0.41 | 0.114 |
| Preoperative aortic insufficiency, cm2 | 9.02 ± 0.28 | 12.20 ± 0.30 | 8.43 ± 0.32 | <0.001 |
| Serum creatinine before surgery, μmol/L | 84.13 ± 1.26 | 105.6 ± 3.92 | 80.15 ± 1.21 | <0.001 |
| Operative | ||||
| In-hospital mortality, n | 32 (6.3%) | 18 (22.5%) | 14 (3.2%) | <0.001 |
| Aortic cross-clamp time, minutes | 97.81 ± 1.56 | 122.8 ± 3.56 | 93.19 ± 1.63 | <0.001 |
| Cardiopulmonary bypass time, minutes | 155.34 ± 2.27 | 209.8 ± 5.80 | 145.3 ± 2.15 | <0.001 |
| Mechanical ventilation time, hours | 55.23 ± 2.42 | 73.2 ± 5.66 | 51.91 ± 2.64 | 0.001 |
| ICU retention time, days | 5.47 ± 0.13 | 7.0 ± 0.19 | 5.19 ± 0.15 | <0.001 |
| Hospitalized time postoperative, days | 19.47 ± 0.38 | 21.2 ± 1.04 | 19.15 ± 0.4 | 0.047 |
| Serum creatinine 24 h after surgery, μmol/L | 98.59 ± 1.96 | 134.8 ± 7.27 | 91.89 ± 1.72 | <0.001 |
| Serum creatinine 48 h after surgery, μmol/L | 116.94 ± 3.06 | 150.2 ± 11.57 | 110.78 ± 2.84 | <0.001 |
| Fluid balance on operation day, ml | −586.88 ± 36.21 | −600.0 ± 48.78 | −584.4 ± 42.0 | 0.876 |
| Fluid balance on 1st day postoperative, ml | −637.50 ± 54.06 | −440.0 ± 63.19 | −674.1 ± 62.85 | 0.116 |
| Fluid balance on 2nd day postoperative, ml | −446.88 ± 34.48 | −200.0 ± 31.82 | −492.6 ± 40.1 | 0.002 |
| Chest drainage, ml | 686.88 ± 15.41 | 786.0 ± 41.14 | 668.5 ± 16.48 | 0.006 |
| Postoperative left ventricular end diastolic dimension, mm | 49.61 ± 0.32 | 55.0 ± 0.64 | 48.58 ± 0.34 | <0.001 |
| Postoperative left ventricular ejection fractions, % | 58.15 ± 0.34 | 55.4 ± 0.78 | 58.68 ± 0.37 | <0.001 |
| Fresh-frozen plasma, ml | 722.81 ± 17.94 | 930.0 ± 36.53 | 684.4 ± 19.62 | <0.001 |
| Packed red cells, units | 2.91 ± 0.12 | 4.20 ± 0.35 | 2.67 ± 0.12 | <0.001 |
| Follow-up | Total (n = 460) | Group with destruction of the aortic annulus (n = 60) | Group without destruction of the aortic annulus (n = 400) | P value |
| Length of follow-up, months | 74.96 ± 2.44 | 36.5 ± 5.6 | 77.8 ± 2.6 | <0.001 |
| All-time mortality, n | 79 (17.2%) | 42 (70%) | 37 (9.3%) | <0.001 |
| All-time re-operation, n | 41 (8.9%) | 18 (30%) | 23 (5.8%) | <0.001 |
ICU, intensive care unit.