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. 2023 Dec 28;80:101868. doi: 10.1016/j.molmet.2023.101868

Figure 5.

Figure 5

ETB deficiency results in increased serum concentration of free thyroxine after a 12-week high-fat diet. Arithmetic means ± SEM of serum concentration of free thyroxine (fT4) (A; n = 4–5 per group) and pituitary thyroid-stimulating hormone, beta subunit (encoded by Tshb) mRNA expression, normalized to TATA-box binding protein (Tbp) (B; n = 4 per group) in wild type mice (etb+/+) and etb−/− mice fed a high-fat diet (HFD) for 12 weeks. ∗p < 0.05 indicates a significant difference from etb+/+ mice. (A: two-tailed unpaired Student's t test; B: two-tailed unpaired Student's t test with Welch's correction) arbitrary units, a.u.