Table 2.

Semi-structured interview guide administered to study participants in Minneapolis, Minnesota between February–August 2022.

Thank you for agreeing to participate in an interview today. As you likely know, your clinic has agreed to take part in study where HPV self-sampling will be offered to patients who are due for cervical cancer screening as an option for completing their screening. This may mean there are some changes that need to happen to make this work well for everyone here. I’m interested in your views about HPV self-sampling and your feedback will be helpful as we plan to implement HPV self-sampling as an option for cervical cancer screening here at the clinic. 1.Before we get started today can you please describe for me a bit about your role at the clinic and how long you have been here? 2.Now I would like to ask you some questions about using methods like HPV self sampling here at the clinic. Can you share what experiences have you had or observed in using patient collected samples in your practice or at this clinic? 3.Have you heard of HPV self sampling for cervical cancer screening before? If no – provide a brief explanation. Prompt: What are your thoughts about HPV self-sampling? 4.What do you think about offering the option of HPV self collected patient samples as part of cervical cancer screening at this clinic? Prompts: Any particular concerns about it? Any particular advantages to using self-sampling? 5.Do you have any thoughts or concerns about the evidence for using HPV SS? Prompts: What else would you want to know more about in relation to HPV SS? Do you feel it offers a the same quality as a Pap test? 6.I would now like to ask you a few questions about how patients might see HPV self-sampling as an option for cervical cancer screening. How do you think Somali patients at this clinic might react to be offered the option of HPV self-sampling for cervical cancer screening? Prompt: Why do you think that?  7.What information or education do you think Somali patients might need as they consider if they want to use the option of HPV self-sampling as an option for cervical cancer screening? 8.How do you imagine other patient populations in your clinic react to the idea of HPV self-sampling? 9.As we plan to implement HPV self-sampling as an option for cervical cancer screening we imagine this could mean there are some changes that need to happen to make this work well for everyone here at the clinic. Based on your role and experience, what do you think needs to happen for HPV self sampling to be successfully offered as an option for cervical cancer screening here? Prompts: Are there structural changes that might be needed? What else do we need to know? 10.We know everyone in the clinic has a part to play in the care workflow. Again based on your role and experience, how would adding the option for HPV self-sampling for cervical cancer screening impact the work you do? 11.Please share with me how you would see HPV self-sampling best fitting into your current workflow around cervical cancer screening? Prompts: Who might offer it? Which role would be best placed to support this? How would it fit into the clinical encounter the best? Where would the sampling be most easily done? 12.How well do you think an approach like HPV SS fits in this setting? Prompts: Do you think there is leadership support?  13.Can you describe for me what kinds of processes are typically used at the clinic for implementing new changes? Prompts: How well do you see that working? What could improve that? 14.When you are making changes, how do you usually get feedback about how well that is going? Prompts: What would work well for getting feedback about this change? 15.What training do you think will be needed for clinic providers or staff to help support implementation of HPV self sampling? 16.How do you feel about HPV self sampling being offered as an option for cervical cancer screening at the clinic? Prompts: How do you feel about the plan to implement the intervention in your setting? Do you have any feelings of anticipation? Stress? Why? 17.How confident are you that you will be able to successfully implement HPV self sampling as an option for cervical cancer screening? 18.How confident do you think your colleagues feel about using the intervention? 19.Do you have any other thoughts you would like to share on how we might best implement HPV self-sampling as an option for cervical cancer screening in primary care?