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. 2024 Jan 3;10(2):e24010. doi: 10.1016/j.heliyon.2024.e24010

Fig. 3.

Fig. 3

TP inhibits pyroptosis in cardiac remodeling models. (A–B) The concentrations of IL-1β and IL-18 in serum (n = 3). (C–D) The concentrations of IL-1β and IL-18 in HL-1 cardiomyocytes (n = 3). (E–H) Western blot analysis of NLRP3, cleaved Caspase-1 and GSDMD protein expression in mouse heart tissue (n = 6). (I–L) Western blot analysis of NLRP3, cleaved Caspase-1 and GSDMD protein expression in HL-1 cardiomyocytes (n = 6). All the values are presented as mean ± SD. #P < 0.05, ##P < 0.01 compared with Sham or Ctl group; *P < 0.05, **P < 0.01 compared with TAC or AngⅡ group. The original blots were provided in supplementary data as Supplementary Fig. S2.