Skip to main content
. 2005 Apr;71(4):1829–1835. doi: 10.1128/AEM.71.4.1829-1835.2005

FIG. 4.

FIG. 4.

Total ion chromatograms (TIC) from HPLC-MS analysis of extracts from fermentation of strains K279-48/pKOS279-69 (A) and K272-166 (B). The positions of geldanamycin and related compounds (as determined by their fragmentation patterns) are indicated. Geldanamycin and its reduced form, 18,21-dihydro-geldanamycin, appeared at about 6.95 and 3.98 min on the chromatogram of strain K279-48/pKOS279-69 with MS peaks at 583 and 585 AMU ([M+Na]+), respectively. KOSN-1869 appeared at about 2.1 min on the chromatogram of strain K272-166 with a base MS peak at 506 AMU ([M+H]+).