Conserved domain search for Cry35Ab1. (A) The Cry35Ab1 protein sequence is indicated by a horizontal line, with blackened ovals indicating the position of two partial alignments of the tripartate beta-trefoil domain similarity (Conserved Domain Database [CDD] entry cd00161) and a white oval indicating a conserved domain based on the B. sphaericus 42-kDa mosquitocidal toxin (CDD entry pfam05431). (B) Multiple-sequence alignment showing two possible alignments of the cd00161 beta-trefoil consensus sequence against the Cry35Ab1 sequence. The QxW motifs of the beta-trefoil sequence are underlined below the consensus line. Lines with arrows denote the internal repeat sequences in the beta-trefoil domain. Consensus similarity groups are the following: 1-D,N; 3-S,T; 4-K,R; 6-L,I,V,M.