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. 2023 Dec 22;6(1):e220127. doi: 10.1148/rycan.220127

Figure 4:

Spearman correlation of mean intracellular pH (pHi) in the whole-tumor volume (WTV) and normal-appearing white matter (NAWM) with respect to (A) proliferation index Ki-67, (B) age, and (C) tumor size for all study participants with glioma (n = 12). (A) Spearman correlation analysis of mean pHi in NAWM and WTV with proliferation index Ki-67 showed no correlation for pHi in NAWM (R2 = 0.01, rS = 0.17, P = .59) and a positive correlation for the pHi within the WTV (R2 = 0.74, rS = 0.78, P = .001). (B) Spearman correlation analysis of mean pHi in NAWM and WTV with age yielded no correlation for NAWM (R2 = 0.08, rS = -0.01, P = .97) and a positive correlation for WTV (R2 = 0.32, rS = 0.60, P = .04). (C) Spearman correlation analysis of mean pHi of the WTV with tumor size showed no correlation (R2 = 0.004, rS = 0.05, P = .87).

Spearman correlation of mean intracellular pH (pHi) in the whole-tumor volume (WTV) and normal-appearing white matter (NAWM) with respect to (A) proliferation index Ki-67, (B) age, and (C) tumor size for all study participants with glioma (n = 12). (A) Spearman correlation analysis of mean pHi in NAWM and WTV with proliferation index Ki-67 showed no correlation for pHi in NAWM (R2 = 0.01, rS = 0.17, P = .59) and a positive correlation for the pHi within the WTV (R2 = 0.74, rS = 0.78, P = .001). (B) Spearman correlation analysis of mean pHi in NAWM and WTV with age yielded no correlation for NAWM (R2 = 0.08, rS = -0.01, P = .97) and a positive correlation for WTV (R2 = 0.32, rS = 0.60, P = .04). (C) Spearman correlation analysis of mean pHi of the WTV with tumor size showed no correlation (R2 = 0.004, rS = 0.05, P = .87).