TABLE 5.
Mononuclear cells expressing the CD4+ and CD8+ phenotypes after stimulation by L. aethiopica antigen
| Cells | Mean ± SD (range) % ina:
|
||
|---|---|---|---|
| Patients | Cured patients | Lab-infected individual | |
| CD4+ | 42.1 ± 17.9 (14.9–72.7) | 28.6 ± 9.9 (19.7–47.1) | 47.7 |
| CD8+ | 18.3 ± 11.9 (2.0–32.3) | 23.3 ± 7.8 (14.9–34.5) | 27 |
| CD16/56+ | 6.1 ± 7.0 (0.0–18.0) | 15.0 ± 15.5 (1.8–43.5) | 16.6 |
a
The percentages of large CD8+ cells in L. aethiopica-stimulated cultures from patients were on average significantly lower (P < 0.05 by Student’s t test) than the CD4+-cell levels, while there was no significant difference between the percentages of CD8+ and CD4+ cells in the cured group.