TABLE 3:

Multiple Sclerosis and Other Demyelinating Diseases Protocol for 7-T Brain MRI With and Without IV Contrast Medium

Sequence	Plane	Slice Thickness (mm)	Matrix	FOV (mm)	Interslice Distance (%)	Voxel Size (mm)	Acq Time (min:s)	TR/TE (ms)	Accel Fac	Interpolation
3D FS T1-weighted MP-RAGE	Sagittal	0.3	224 × 224	150	50	0.3 × 0.3 × 0.3	6:32	3000/2.42	GRAPPA 3	Yes
FS FLAIR	Axial	2.0	320 × 256	220	20	0.7 × 0.7 × 2.0	3:38	9000/74	GRAPPA 3	No
3D FLAIR SPACE	Sagittal	0.8	192 × 173	160	NA	0.8 × 0.8 × 0.8	7:14	9000/249	GRAPPA 3	No
3D DIR SPACE	Sagittal	0.9	160 × 160	170	NA	0.5 × 0.5 × 0.9	8:26	8000/321	GRAPPA 2	Yes
FS T2-weighted TSEa	Axial	1.5	704 × 704	210	30	0.1 × 0.1 × 1.5	6:08 (×2)	3900/61	GRAPPA 3	Yes
SWI	Axial	1.4	640 × 640	220	20	0.2 × 0.2 × 14	6:28	22/15	GRAPPA 3	Yes
After IV injection of contrast medium (0.05 mL/kg) followed by normal saline flush (10 mL) IV, both at 2 mL/s
DWI RESOLVE	Sagittal	2.0	192 × 144	230	20	1.2 × 1.2 × 2.0	2:49	6200/46 and 72	Slice accel 3	No
3D FS T1-weighted MP-RAGE	Sagittal	0.3	224 × 224	150	50	0.3 × 0.3 × 0.3	6:32	3000/2.42	GRAPPA 3	Yes

Note—Total acquisition time is approximately 54 minutes. Acq = acquisition, Accel Fac = acceleration factor, FS = fat-saturated, NA= not applicable, DIR = dual inversion recovery, TSE = turbo spin-echo, SWI = susceptibility-weighted imaging, RESOLVE = readout segmentation of long variable echo trains, accel = acceleration.

^aTwo separate acquisitions of the upper and lower brain.