Table 2.

Clinical trial timeline assumptions in weeks.

Study Phase	Registry-Based Trial	Pragmatic Trial	Explanatory Trial
Planning	52	52	52
Enrollment	156	156	156
Treatment	4.3	4.3	4.3
Follow-up	4.3	4.3	4.3
Database lock delay	20.7	0.0	0.0
Sites closed	4.3	4.3	4.3
Statistical Report	4	4	4
Reports and Dissemination	14	2.7	2.7
Total Weeks Duration	259.5	227.6	227.6