Figure 6.

5xFADxTg30 mice have altered lipidome in both periphery and brain

Linear regression examining the fold difference in lipid class totals between WT and 5xFADxTg30 mice in (A) plasma and (B) brain. Fold differences are presented on a log2 scale such that ‘2’ means 2 times higher in 5xFADxTg30 relative to WT and the equivalent for the inverse (where 5xFADxTg30 is half of WT) is 0.5. Non-filled diamond, uncorrected p value >0.05, Colored diamonds, nominal p value <0.05, black diamond with colored outline, FDR corrected p < 0.05. All results in Tables S1 and S2.