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. 2024 Jan 4;27(2):108800. doi: 10.1016/j.isci.2024.108800

Figure 8.

Figure 8

Characterization of brain and biomarker pathology associated with APP and tau

(A) Total tau western images and densitometry, (B) phosphorylated tau (Ser202/Thr205) western images and densitometry, (C) APP protein levels and densitometry, and (D) Amyloid β expression levels and densitometry in male and female mice, n = 5–7. Brain tissue obtained from the hippocampus, “MW” indicates molecular weight marker.

(E) Plasma neurofilament light (NFL) levels, n = 4–5. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p = <0.001 data assessed by a Student’s t test or two-way ANOVA. Graphs indicate mean ± SEM.