Table 1.
Clinical characteristics of COVID-19 in pregnant women.
| Subject (case, %) | Total (n = 1,024) | Doses of vaccine | Statistical value | P | ||||
|---|---|---|---|---|---|---|---|---|
| (A) 0 dose (n = 317) | (B) 1 dose (n = 56) | (C) 2 doses (n = 546) | (D) 3 doses (n = 105) | |||||
| Age (years)# | χ2 = 3.831 | 0.2803 | ||||||
| 18–34 | 849 (82.9) | 255 (80.4) | 46 (82.1) | 455 (83.3) | 93 (88.6) | |||
| ≥35 | 175 (17.1) | 62 (19.6) | 10 (17.9) | 91 (16.7) | 12 (11.4) | |||
| Pregnancy stage# | χ2 = 113.4 | < 0.0001 | ||||||
| Early | 282 (27.5) | 58 (18.3) | 12 (21.4) | 146 (26.7) | 66 (62.9) | χ2 = 80.43 | < 0.0001 | |
| Middle | 276 (27.0) | 74 (23.3) | 17 (30.4) | 150 (27.5) | 35 (33.3) | χ2 = 4.673 | 0.1974 | |
| Late | 466 (45.5) | 185 (58.4) | 27 (48.2) | 250 (45.8) | 4 (3.8) | χ2 = 94.92 | < 0.0001 | |
| Pregnancy risk a | χ2 = 3.149 | 0.7899 | ||||||
| Purple + green | 535 (52.2) | 164 (51.7) | 30 (53.6) | 278 (50.9) | 63 (60.0) | χ2 = 2.990 | 0.3931 | |
| Purple + yellow | 379 (37.0) | 117 (36.9) | 20 (35.7) | 209 (38.3) | 33 (31.4) | χ2 = 1.822 | 0.6102 | |
| Purple + orange | 110 (10.7) | 36 (11.4) | 6 (10.7) | 59 (10.8) | 9 (8.6) | χ2 = 0.643 | 0.8865 | |
| Clinical manifestations# | ||||||||
| Asymptomatic | 865 (84.5) | 263 (83.0) | 49 (87.5) | 461 (84.4) | 92 (87.6) | χ2 = 0.973 | 0.6147 | |
| Mild b | 157 (15.3) | 54 (17.0) | 7 (12.5) | 83 (15.2) | 13 (12.4) | χ2 = 0.772 | 0.6798 | |
| Moderate b | 2 (0.2) | 0 (0) | 0 (0) | 2 (0.2) | 0 (0) | – | >0.9999 | |
| Clinical symptoms# | ||||||||
| Fever | 38 (3.7) | 14 (4.4) | 0 (0) | 21 (3.8) | 3 (2.9) | – | 0.4747 | |
| Coughing/difficulty breathing | 62 (6.1) | 21 (6.6) | 1 (1.8) | 33 (6.0) | 7 (6.7) | – | 0.6708 | |
| Vomiting | 8 (0.8) | 3 (0.9) | 0 (0) | 5 (0.9) | 0 (0) | – | 0.7085 | |
| Diarrhea | 2 (0.2) | 1 (0.3) | 0 (0) | 1 (0.2) | 0 (0) | – | 0.5235 | |
| Rashes | 5 (4.9) | 3 (0.9) | 0 (0) | 1 (0.2) | 1 (0.9) | – | 0.1755 | |
| Image changes# | 2 (0.2) | 0 (0) | 0 (0) | 2 (0.2) | 0 (0) | – | >0.9999 | |
#The data were collected upon admission.
-Comparison between the vaccinated and unvaccinated groups
a
The National Health and Family Planning Commission has released a female pregnancy risk assessment table, which is divided into five colors according to the severity of the risk: green (low risk), yellow (general risk), orange (high-risk), red (extremely high-risk), and purple (infectious disease).
b
The definition of “mild” was stated as mild clinical symptoms without any alterations in the computed tomography (CT) images; The definition of “moderate” was assigned as mild clinical symptoms accompanied by alterations in CT images.