Fig. 3.

The Modulation of the Inflammatory Program in Activated Macrophages by OBE. (a) Gene ontology enrichment analysis of DEG modulated by OBE in human and mouse macrophages. The coloured bars represent the percentage of genes present in the data set compared to the total number of genes in each term (% Genes/Term). The down-regulated and up-regulated ontologies are shown in blue and red, respectively. (b) Bar plots of normalised differentially expressed genes with a critical function on inflammation: Cytokines, chemokines, and inflammatory mediators. *p ≤ 0.05 compared with AC. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)