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Simplified overview of a selection of key pathways and mediators in CVD and SD.
ECM: extracellular matrix; ICAM-1: intracellular adhesion molecule 1; MCP-1: monocyte chemoattractant protein 1; MMP: matrix metalloproteinase; ROS: reactive oxygen species; TIMP: tissue inhibitor of metalloproteinase; TNF-α: tumor necrosis factor alpha; VCAM-1: vascular cell adhesion molecule 1
