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. Author manuscript; available in PMC: 2024 Jan 30.
Published in final edited form as: J Neurochem. 2019 Dec 10;152(5):556–569. doi: 10.1111/jnc.14914

Figure 5.

Figure 5

Top Panel: Mean (+SEM) number of self-infusions of EtOH during the first 4 ICSA sessions by rats pretreated with 7 microinjection sessions of aCSF, EtOH, NIC, or EtOH+NIC (n = 4–8 animals/group). Middle Panel: Mean (+SEM) number of self-infusions of EtOH during the first 4 ICSA sessions by rats pretreated with 7 microinjection sessions of aCSF or BDNF (n = 6–8 animals/group). Bottom Panel: Mean (+SEM) number of self-infusions of a subthreshold EtOH dose during the first 4 ICSA sessions by control rats pretreated with a single microinjection session of aCSF, EtOH+NIC, or BDNF (n = 8 animals/group). Asterisk (*) indicates significantly more self-infusions of 75 mg% EtOH compared to all other pretreatment groups. Plus sign (+) indicates significantly more self-infusions than corresponding pretreatment groups allowed to self-administer aCSF.