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[Preprint]. 2024 Jan 16:2024.01.15.575715. [Version 1] doi: 10.1101/2024.01.15.575715

Table 2.

Comparison of MSD ELISA detection of p-S65-Ub with different testing materials

Fold change in MSD ELISA detection ref. Ab 11H2K3 19H1K1 29H2K2 30H3K1 41H1K3

HEK293E cells baseline detection (WT vs. PINK1 KO) 2.1 1.3 1.8 1.1 1.4 1.1
HEK293E cells stressed condition (treated WT vs. PINK1 KO) 143.5 52 91.2 5.6 80.2 4.8
Mouse brain baseline detection (WT vs. pinkl KO) 1.5 1.1 1.6 1 1.2 1
Human brain disease condition (control vs. AD) 9.3 10.8 2.6 4.9 3.7 2

WT - wild-type, KO - knockout, AD - Alzheimer disease.