Figure 4:

ICP0 dimer arrangement. A) Subunit A showing helices (cyan), β-strands (magenta), and loops (gray). B) Subunit B added with helices (green), β-strands (tan), and loops (blue). The β3 strand intertwines with its counterpart, β3’. View is along the non-crystallographic 2-fold axis. Panels C and D are views perpendicular to the non-crystallographic 2-fold axis. E) Anti-parallel β-strand interactions are formed between β3-β3’ and β4-β4’. F) β3’ and β4’ of subunit B are inserted between β2 and β5 of subunit A to form a nine-strand β-barrel-like structure.