Table 3B:

Outcome of MRLap sensitivity analysis

Trait	Exposure	Outcome	No. of instruments	Observed Beta	P	Corr. Beta	Corr. P
Neuroticism	MDD	Neuro	61	0.784	5.85E-57	0.94	4.17e-56
	Neuro	MDD	64	0.445	2.00E-61	0.529	6.04E-49
	ANX	Neuro	58	0.303	4.78E-14	0.531	7.781E-14
	Neuro	ANX	102	0.471	3.12E-46	0.548	1.13E-40
Agreeableness	MDD	Agree	70	−0.321	3.64E-11	−0.396	2.94E-10
	Agree	MDD	33	−0.15	3.73E-04	−0.373	8.85E-04
	ANX	Agree	58	−0.241	2.90E-13	−0.350	1.76E-08
	Agree	ANX	24	−0.297	6.88E-05	−0.662	1.77E-02