FIG. 2.

Effect of treatment with IFN-γ before SINV infection. Cycling undifferentiated CSM14.1 cells and 1-, 2-, and 3-week differentiated CSM14.1 (dCSM) cells were treated with 100 U of IFN-γ/ml 24 h before infection and analyzed for cell viability by trypan blue exclusion (A) and SINV replication over 7 days (B) and over 3 days in 3-week differentiated cells (C). Cells were infected with SINV-eGFP at an MOI of 1. Cell viability was improved and virus replication was reduced in all groups compared to untreated cells (*, P < 0.05; **, P < 0.01; ***, P < 0.001; Student's t test). The dashed line indicates the limit of virus detection.