Table 4.
Multivariable analysis of OS and EFS
| EFS |
OS |
||||
|---|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | ||
| Conditioning regimen | Flu/Thio/Bu | 1 | 1 | ||
| Flu/Thio/Treo | 0.94 (0.60-1.46) | .769 | 0.64 (0.37-1.13) | .124 | |
| Donor | MSD | 1 | 1 | ||
| MUD | 1.31 (0.71-2.42) | .388 | 3 (0.51-2.10) | .928 | |
| Remission status | CR1 | 1 | 1 | ||
| ≥CR2 | 1.49 (0.88-2.52) | .136 | 1.44 (0.75-2.76) | .271 | |
| Immunophenotype | BCP | 1 | 1 | ||
| T-cell ALL | 0.81 (0.37-1.78) | .603 | 0.98 (0.38-2.49) | .964 | |
| Other | NA∗ | NA∗ | NA∗ | NA∗ | |
| Age at HSCT, y | <2 | 1 | 1 | ||
| >2 to ≥4 | 1.23 (0.74-2.08) | .403 | 1.42 (0.62-3.22) | .405 | |
| KMT2A-AFF1 | No | 1 | 1 | ||
| Yes | 1.25 (0.74-2.08) | .403 | 1.96 (1.05-3.68) | .036 | |
| Age at diagnosis, y | <1 | 1 | 1 | ||
| ≥1 | 0.49 (0.25-0.99) | .046 | 0.70 (0.31-1.59) | .397 | |
∗
No estimates or P values are given because of limited sample size in this subgroup (6 patients and 0 events).